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Sub-process irradiation of naturally contaminated hypodermic needles

Identifieur interne : 006D23 ( Main/Exploration ); précédent : 006D22; suivant : 006D24

Sub-process irradiation of naturally contaminated hypodermic needles

Auteurs : P. T. Doolan [États-Unis] ; N. A. Halls [Irlande (pays)] ; A. Tallentire [Royaume-Uni]

Source :

Abstract

The proportion of nonsterile hypodermic needles within a population of needles (P), contaminated initially with native microflora, has been measured as a function of gamma-radiation dose (D) over the range 0 – 4 kGy. The relationship between P and D was regular and allowed extrapolation to higher doses corresponding to the generally accepted probability of occurence of a nonsterile item or sterility assurance level (SAL), and beyond. An absorbed dose of 7.5 kGy was estimated to be sufficient to give a value of P of 10-6, whereas a dose of 25 kGy would be expected to give a P of 10-18.


Url:
DOI: 10.1016/1359-0197(88)90247-0


Affiliations:


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