La thérapie familiale en francophonie (serveur d'exploration)

Attention, ce site est en cours de développement !
Attention, site généré par des moyens informatiques à partir de corpus bruts.
Les informations ne sont donc pas validées.

Longitudinal study of behavioral and affective patterns in girls with central precocious puberty during long‐acting triptorelin therapy

Identifieur interne : 000089 ( Belgique/Analysis ); précédent : 000088; suivant : 000090

Longitudinal study of behavioral and affective patterns in girls with central precocious puberty during long‐acting triptorelin therapy

Auteurs : D. Xhrouet-Heinrichs ; K. Lagrou ; C. Heinrichs [Belgique] ; M. Craen [Belgique] ; L. Dooms [Belgique] ; P. Malvaux [Belgique] ; F. Kanen [Belgique] ; J-P Bourguignon [Belgique]

Source :

RBID : ISTEX:2F9C9FF04060C24F822B90B6B15767FC26C5ADEF

Mots-clés :

Abstract

Abstract The aim of the present study was to evaluate the behavioral and affective characteristics and the changes in psychosocial functioning resulting from precocious puberty in 15 girls with central precocious puberty treated for 2 y using the GnRH agonist long‐acting triptorelin, and in 5 untreated girls. After diagnosis of precocious puberty at 6.6–10.4 y of age, height, weight and pubertal development were evaluated at 3‐month intervals over 2 y. Semi‐structured interviews were carried out with the patient, the parents and the pediatric endocrinologists at 1, 8, 16 and 24 months after diagnosis. Standardized questionnaires (Child Behavior Checklist, Self‐esteem Inventory) were administered at 1 and 24 months or 16 and 24 months, respectively. There was a mean 1.5‐y delay between the observation of signs of puberty as reported by the parents and the diagnosis of precocious puberty at the first consultation of a pediatric endocrinologist. Before follow‐up, all 20 girls were very concerned about physical differences from peers, particularly breast development. During therapy, breast regression to minimal or absent development occurred in 5/15 treated patients, who then no longer felt embarrassed about pubertal development in contrast to the other patients. Fear of sexuality remained obvious throughout the study in most patients. Feelings of loneliness and exemplary behavior were observed and tended to decrease in the treated patients and to increase in the untreated patients. Elevated scores of withdrawal, anxiety/depression and somatic complaints at Child Behavior Checklist were still observed after 2 y. These changes in behavioral and affective characteristics appeared to be related neither to height and weight, nor to development of pubic hair, which progressed in most patients. After 2 y, the physical differences remained a concern for 13 girls and the risk of short adult stature for 6. In summary, some behavioral and affective characteristics and particularities in psychosocial functioning are observed in girls with precocious puberty. During treatment with long acting triptorelin, problematic behavior and functioning decrease slightly, particularly in the few girls showing breast regression to minimal or absent development.


Url:
DOI: 10.1111/j.1651-2227.1997.tb08602.x


Affiliations:


Links toward previous steps (curation, corpus...)


Links to Exploration step

ISTEX:2F9C9FF04060C24F822B90B6B15767FC26C5ADEF

Le document en format XML

<record>
<TEI wicri:istexFullTextTei="biblStruct">
<teiHeader>
<fileDesc>
<titleStmt>
<title xml:lang="en">Longitudinal study of behavioral and affective patterns in girls with central precocious puberty during long‐acting triptorelin therapy</title>
<author>
<name sortKey="Xhrouet Einrichs, D" sort="Xhrouet Einrichs, D" uniqKey="Xhrouet Einrichs D" first="D" last="Xhrouet-Heinrichs">D. Xhrouet-Heinrichs</name>
</author>
<author>
<name sortKey="Lagrou, K" sort="Lagrou, K" uniqKey="Lagrou K" first="K" last="Lagrou">K. Lagrou</name>
</author>
<author>
<name sortKey="Heinrichs, C" sort="Heinrichs, C" uniqKey="Heinrichs C" first="C" last="Heinrichs">C. Heinrichs</name>
</author>
<author>
<name sortKey="Craen, M" sort="Craen, M" uniqKey="Craen M" first="M" last="Craen">M. Craen</name>
</author>
<author>
<name sortKey="Dooms, L" sort="Dooms, L" uniqKey="Dooms L" first="L" last="Dooms">L. Dooms</name>
</author>
<author>
<name sortKey="Malvaux, P" sort="Malvaux, P" uniqKey="Malvaux P" first="P" last="Malvaux">P. Malvaux</name>
</author>
<author>
<name sortKey="Kanen, F" sort="Kanen, F" uniqKey="Kanen F" first="F" last="Kanen">F. Kanen</name>
</author>
<author>
<name sortKey="Bourguignon, J" sort="Bourguignon, J" uniqKey="Bourguignon J" first="J-P" last="Bourguignon">J-P Bourguignon</name>
</author>
</titleStmt>
<publicationStmt>
<idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:2F9C9FF04060C24F822B90B6B15767FC26C5ADEF</idno>
<date when="1997" year="1997">1997</date>
<idno type="doi">10.1111/j.1651-2227.1997.tb08602.x</idno>
<idno type="url">https://api.istex.fr/document/2F9C9FF04060C24F822B90B6B15767FC26C5ADEF/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">000122</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000122</idno>
<idno type="wicri:Area/Istex/Curation">000122</idno>
<idno type="wicri:Area/Istex/Checkpoint">000D62</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000D62</idno>
<idno type="wicri:doubleKey">0803-5253:1997:Xhrouet Einrichs D:longitudinal:study:of</idno>
<idno type="wicri:Area/Main/Merge">001149</idno>
<idno type="wicri:Area/Main/Curation">001132</idno>
<idno type="wicri:Area/Main/Exploration">001132</idno>
<idno type="wicri:Area/Belgique/Extraction">000089</idno>
</publicationStmt>
<sourceDesc>
<biblStruct>
<analytic>
<title level="a" type="main" xml:lang="en">Longitudinal study of behavioral and affective patterns in girls with central precocious puberty during long‐acting triptorelin therapy</title>
<author>
<name sortKey="Xhrouet Einrichs, D" sort="Xhrouet Einrichs, D" uniqKey="Xhrouet Einrichs D" first="D" last="Xhrouet-Heinrichs">D. Xhrouet-Heinrichs</name>
<affiliation>
<wicri:noCountry code="no comma">in collaboration with the Belgian Study Group for Pediatric Endocrinology</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Lagrou, K" sort="Lagrou, K" uniqKey="Lagrou K" first="K" last="Lagrou">K. Lagrou</name>
<affiliation>
<wicri:noCountry code="no comma">in collaboration with the Belgian Study Group for Pediatric Endocrinology</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Heinrichs, C" sort="Heinrichs, C" uniqKey="Heinrichs C" first="C" last="Heinrichs">C. Heinrichs</name>
<affiliation wicri:level="1">
<country xml:lang="fr">Belgique</country>
<wicri:regionArea>Department of Pediatrics</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Craen, M" sort="Craen, M" uniqKey="Craen M" first="M" last="Craen">M. Craen</name>
<affiliation wicri:level="1">
<country xml:lang="fr">Belgique</country>
<wicri:regionArea>Department of Pediatrics</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Dooms, L" sort="Dooms, L" uniqKey="Dooms L" first="L" last="Dooms">L. Dooms</name>
<affiliation wicri:level="1">
<country xml:lang="fr">Belgique</country>
<wicri:regionArea>Department of Pediatrics</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Malvaux, P" sort="Malvaux, P" uniqKey="Malvaux P" first="P" last="Malvaux">P. Malvaux</name>
<affiliation wicri:level="1">
<country xml:lang="fr">Belgique</country>
<wicri:regionArea>Department of Pediatrics</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Kanen, F" sort="Kanen, F" uniqKey="Kanen F" first="F" last="Kanen">F. Kanen</name>
<affiliation wicri:level="1">
<country xml:lang="fr">Belgique</country>
<wicri:regionArea>Department of Pediatrics</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Bourguignon, J" sort="Bourguignon, J" uniqKey="Bourguignon J" first="J-P" last="Bourguignon">J-P Bourguignon</name>
<affiliation wicri:level="1">
<country xml:lang="fr">Belgique</country>
<wicri:regionArea>Department of Pediatrics</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1">
<country xml:lang="fr">Belgique</country>
<wicri:regionArea>Division of Pediatric and Adolescent Medicine, C.H.U. Sart Tilman, B‐4000 Liège</wicri:regionArea>
<wicri:noRegion>B‐4000 Liège</wicri:noRegion>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series>
<title level="j">Acta Pædiatrica</title>
<idno type="ISSN">0803-5253</idno>
<idno type="eISSN">1651-2227</idno>
<imprint>
<publisher>Blackwell Publishing Ltd</publisher>
<pubPlace>Oxford, UK</pubPlace>
<date type="published" when="1997-08">1997-08</date>
<biblScope unit="volume">86</biblScope>
<biblScope unit="issue">8</biblScope>
<biblScope unit="page" from="808">808</biblScope>
<biblScope unit="page" to="815">815</biblScope>
</imprint>
<idno type="ISSN">0803-5253</idno>
</series>
<idno type="istex">2F9C9FF04060C24F822B90B6B15767FC26C5ADEF</idno>
<idno type="DOI">10.1111/j.1651-2227.1997.tb08602.x</idno>
<idno type="ArticleID">APA808</idno>
</biblStruct>
</sourceDesc>
<seriesStmt>
<idno type="ISSN">0803-5253</idno>
</seriesStmt>
</fileDesc>
<profileDesc>
<textClass>
<keywords scheme="KwdEn" xml:lang="en">
<term>GnRH agonist</term>
<term>precocious puberty</term>
<term>psychological aspects</term>
</keywords>
</textClass>
<langUsage>
<language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front>
<div type="abstract">Abstract The aim of the present study was to evaluate the behavioral and affective characteristics and the changes in psychosocial functioning resulting from precocious puberty in 15 girls with central precocious puberty treated for 2 y using the GnRH agonist long‐acting triptorelin, and in 5 untreated girls. After diagnosis of precocious puberty at 6.6–10.4 y of age, height, weight and pubertal development were evaluated at 3‐month intervals over 2 y. Semi‐structured interviews were carried out with the patient, the parents and the pediatric endocrinologists at 1, 8, 16 and 24 months after diagnosis. Standardized questionnaires (Child Behavior Checklist, Self‐esteem Inventory) were administered at 1 and 24 months or 16 and 24 months, respectively. There was a mean 1.5‐y delay between the observation of signs of puberty as reported by the parents and the diagnosis of precocious puberty at the first consultation of a pediatric endocrinologist. Before follow‐up, all 20 girls were very concerned about physical differences from peers, particularly breast development. During therapy, breast regression to minimal or absent development occurred in 5/15 treated patients, who then no longer felt embarrassed about pubertal development in contrast to the other patients. Fear of sexuality remained obvious throughout the study in most patients. Feelings of loneliness and exemplary behavior were observed and tended to decrease in the treated patients and to increase in the untreated patients. Elevated scores of withdrawal, anxiety/depression and somatic complaints at Child Behavior Checklist were still observed after 2 y. These changes in behavioral and affective characteristics appeared to be related neither to height and weight, nor to development of pubic hair, which progressed in most patients. After 2 y, the physical differences remained a concern for 13 girls and the risk of short adult stature for 6. In summary, some behavioral and affective characteristics and particularities in psychosocial functioning are observed in girls with precocious puberty. During treatment with long acting triptorelin, problematic behavior and functioning decrease slightly, particularly in the few girls showing breast regression to minimal or absent development.</div>
</front>
</TEI>
<affiliations>
<list>
<country>
<li>Belgique</li>
</country>
</list>
<tree>
<noCountry>
<name sortKey="Lagrou, K" sort="Lagrou, K" uniqKey="Lagrou K" first="K" last="Lagrou">K. Lagrou</name>
<name sortKey="Xhrouet Einrichs, D" sort="Xhrouet Einrichs, D" uniqKey="Xhrouet Einrichs D" first="D" last="Xhrouet-Heinrichs">D. Xhrouet-Heinrichs</name>
</noCountry>
<country name="Belgique">
<noRegion>
<name sortKey="Heinrichs, C" sort="Heinrichs, C" uniqKey="Heinrichs C" first="C" last="Heinrichs">C. Heinrichs</name>
</noRegion>
<name sortKey="Bourguignon, J" sort="Bourguignon, J" uniqKey="Bourguignon J" first="J-P" last="Bourguignon">J-P Bourguignon</name>
<name sortKey="Bourguignon, J" sort="Bourguignon, J" uniqKey="Bourguignon J" first="J-P" last="Bourguignon">J-P Bourguignon</name>
<name sortKey="Craen, M" sort="Craen, M" uniqKey="Craen M" first="M" last="Craen">M. Craen</name>
<name sortKey="Dooms, L" sort="Dooms, L" uniqKey="Dooms L" first="L" last="Dooms">L. Dooms</name>
<name sortKey="Kanen, F" sort="Kanen, F" uniqKey="Kanen F" first="F" last="Kanen">F. Kanen</name>
<name sortKey="Malvaux, P" sort="Malvaux, P" uniqKey="Malvaux P" first="P" last="Malvaux">P. Malvaux</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Psychologie/corpus/TherFamFrancoV1/Data/Belgique/Analysis
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000089 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Psychologie
   |area=    TherFamFrancoV1
   |flux=    Belgique
   |étape=   Analysis
   |type=    RBID
   |clé=     ISTEX:2F9C9FF04060C24F822B90B6B15767FC26C5ADEF
   |texte=   Longitudinal study of behavioral and affective patterns in girls with central precocious puberty during long‐acting triptorelin therapy
}}

Wicri

This area was generated with Dilib version V0.6.29.
Data generation: Tue May 16 11:23:40 2017. Site generation: Thu Jul 20 16:14:43 2017