[Cardiac metastasis of poorly differentiated adenocarcinoma of unknown primary site].
Identifieur interne : 001F95 ( Main/Exploration ); précédent : 001F94; suivant : 001F96[Cardiac metastasis of poorly differentiated adenocarcinoma of unknown primary site].
Auteurs : Gianluigi Mazzoccoli [Italie] ; Stefano Carughi ; Marco La Viola ; Angelo De Cata ; Felice Puzzolante ; Antonio Camagna ; Aldo Russo ; Sergio CaparrottiSource :
- Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology [ 1129-4728 ] ; 2002.
English descriptors
- KwdEn :
- Adenocarcinoma (diagnosis), Adenocarcinoma (secondary), Adenocarcinoma (therapy), Antineoplastic Combined Chemotherapy Protocols (therapeutic use), Echocardiography, Heart Neoplasms (diagnosis), Heart Neoplasms (secondary), Heart Neoplasms (therapy), Humans, Male, Middle Aged, Neoplasms, Unknown Primary (pathology), Tomography, X-Ray Computed.
- MESH :
- diagnosis : Adenocarcinoma, Heart Neoplasms.
- pathology : Neoplasms, Unknown Primary.
- secondary : Adenocarcinoma, Heart Neoplasms.
- therapeutic use : Antineoplastic Combined Chemotherapy Protocols.
- therapy : Adenocarcinoma, Heart Neoplasms.
- Echocardiography, Humans, Male, Middle Aged, Tomography, X-Ray Computed.
Abstract
The finding of intracardiac masses is very uncommon. In this patient the early clinical picture was characterized by neurologic signs and symptoms as mild forgetfulness, blurred vision, a sensation of imbalance, anorexia, weight loss. Brain magnetic resonance imaging showed multiple metastatic lesions, computed tomography of the chest, abdomen and pelvis showed intraatrial masses and whole body nuclear scanning evidenced bone lesion. It was not possible to find the primary tumor by other instrumental or laboratory exams. Transesophageal echocardiography showed a mass originating from interatrial septum, with atrial invasion and risk of embolization from the left atrium. The patient was transferred to the operating room for cardiac surgery, the mass at risk for embolization was resected and the specimen consisted of fibrous and fibrino-necrotic tissue infiltrated by poorly differentiated adenocarcinoma. The patient received brain and bone radiotherapy and chemotherapy with cisplatin and vinorelbin.
PubMed: 12506513
Affiliations:
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Le document en format XML
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<author><name sortKey="Mazzoccoli, Gianluigi" sort="Mazzoccoli, Gianluigi" uniqKey="Mazzoccoli G" first="Gianluigi" last="Mazzoccoli">Gianluigi Mazzoccoli</name>
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<country wicri:rule="url">Italie</country>
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<author><name sortKey="Carughi, Stefano" sort="Carughi, Stefano" uniqKey="Carughi S" first="Stefano" last="Carughi">Stefano Carughi</name>
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<author><name sortKey="La Viola, Marco" sort="La Viola, Marco" uniqKey="La Viola M" first="Marco" last="La Viola">Marco La Viola</name>
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<author><name sortKey="Camagna, Antonio" sort="Camagna, Antonio" uniqKey="Camagna A" first="Antonio" last="Camagna">Antonio Camagna</name>
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<author><name sortKey="Russo, Aldo" sort="Russo, Aldo" uniqKey="Russo A" first="Aldo" last="Russo">Aldo Russo</name>
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<author><name sortKey="Caparrotti, Sergio" sort="Caparrotti, Sergio" uniqKey="Caparrotti S" first="Sergio" last="Caparrotti">Sergio Caparrotti</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">[Cardiac metastasis of poorly differentiated adenocarcinoma of unknown primary site].</title>
<author><name sortKey="Mazzoccoli, Gianluigi" sort="Mazzoccoli, Gianluigi" uniqKey="Mazzoccoli G" first="Gianluigi" last="Mazzoccoli">Gianluigi Mazzoccoli</name>
<affiliation wicri:level="1"><nlm:affiliation>Divisione di Medicina Interna IRCCS Casa Sollievo della Sofferenza Opera di Padre Pio da Pietrelcina Viale dei Cappuccini 71013 San Giovanni Rotondo, FG. g.mazzoccoli@tin.it</nlm:affiliation>
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<author><name sortKey="Carughi, Stefano" sort="Carughi, Stefano" uniqKey="Carughi S" first="Stefano" last="Carughi">Stefano Carughi</name>
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<author><name sortKey="La Viola, Marco" sort="La Viola, Marco" uniqKey="La Viola M" first="Marco" last="La Viola">Marco La Viola</name>
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<author><name sortKey="De Cata, Angelo" sort="De Cata, Angelo" uniqKey="De Cata A" first="Angelo" last="De Cata">Angelo De Cata</name>
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<author><name sortKey="Puzzolante, Felice" sort="Puzzolante, Felice" uniqKey="Puzzolante F" first="Felice" last="Puzzolante">Felice Puzzolante</name>
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<author><name sortKey="Camagna, Antonio" sort="Camagna, Antonio" uniqKey="Camagna A" first="Antonio" last="Camagna">Antonio Camagna</name>
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<author><name sortKey="Russo, Aldo" sort="Russo, Aldo" uniqKey="Russo A" first="Aldo" last="Russo">Aldo Russo</name>
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<author><name sortKey="Caparrotti, Sergio" sort="Caparrotti, Sergio" uniqKey="Caparrotti S" first="Sergio" last="Caparrotti">Sergio Caparrotti</name>
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<series><title level="j">Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology</title>
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<imprint><date when="2002" type="published">2002</date>
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<term>Adenocarcinoma (secondary)</term>
<term>Adenocarcinoma (therapy)</term>
<term>Antineoplastic Combined Chemotherapy Protocols (therapeutic use)</term>
<term>Echocardiography</term>
<term>Heart Neoplasms (diagnosis)</term>
<term>Heart Neoplasms (secondary)</term>
<term>Heart Neoplasms (therapy)</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Neoplasms, Unknown Primary (pathology)</term>
<term>Tomography, X-Ray Computed</term>
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<term>Heart Neoplasms</term>
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<term>Heart Neoplasms</term>
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<term>Heart Neoplasms</term>
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<keywords scheme="MESH" xml:lang="en"><term>Echocardiography</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Tomography, X-Ray Computed</term>
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<front><div type="abstract" xml:lang="en">The finding of intracardiac masses is very uncommon. In this patient the early clinical picture was characterized by neurologic signs and symptoms as mild forgetfulness, blurred vision, a sensation of imbalance, anorexia, weight loss. Brain magnetic resonance imaging showed multiple metastatic lesions, computed tomography of the chest, abdomen and pelvis showed intraatrial masses and whole body nuclear scanning evidenced bone lesion. It was not possible to find the primary tumor by other instrumental or laboratory exams. Transesophageal echocardiography showed a mass originating from interatrial septum, with atrial invasion and risk of embolization from the left atrium. The patient was transferred to the operating room for cardiac surgery, the mass at risk for embolization was resected and the specimen consisted of fibrous and fibrino-necrotic tissue infiltrated by poorly differentiated adenocarcinoma. The patient received brain and bone radiotherapy and chemotherapy with cisplatin and vinorelbin.</div>
</front>
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<affiliations><list><country><li>Italie</li>
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<tree><noCountry><name sortKey="Camagna, Antonio" sort="Camagna, Antonio" uniqKey="Camagna A" first="Antonio" last="Camagna">Antonio Camagna</name>
<name sortKey="Caparrotti, Sergio" sort="Caparrotti, Sergio" uniqKey="Caparrotti S" first="Sergio" last="Caparrotti">Sergio Caparrotti</name>
<name sortKey="Carughi, Stefano" sort="Carughi, Stefano" uniqKey="Carughi S" first="Stefano" last="Carughi">Stefano Carughi</name>
<name sortKey="De Cata, Angelo" sort="De Cata, Angelo" uniqKey="De Cata A" first="Angelo" last="De Cata">Angelo De Cata</name>
<name sortKey="La Viola, Marco" sort="La Viola, Marco" uniqKey="La Viola M" first="Marco" last="La Viola">Marco La Viola</name>
<name sortKey="Puzzolante, Felice" sort="Puzzolante, Felice" uniqKey="Puzzolante F" first="Felice" last="Puzzolante">Felice Puzzolante</name>
<name sortKey="Russo, Aldo" sort="Russo, Aldo" uniqKey="Russo A" first="Aldo" last="Russo">Aldo Russo</name>
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<country name="Italie"><noRegion><name sortKey="Mazzoccoli, Gianluigi" sort="Mazzoccoli, Gianluigi" uniqKey="Mazzoccoli G" first="Gianluigi" last="Mazzoccoli">Gianluigi Mazzoccoli</name>
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