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<server>
  <NO>: PASCAL 00-0205064 INIST</NO>
  <ET>Application of the 'snapshot' methodology to a basin-wide analysis of phosphorus and nitrogen at stable low flow</ET>
  <AU>SALVIA (M.); IFFLY (J. F.); VANDER BORGHT (P.); SARY (M.); HOFFMANN (L.); GARNIER (Josette); MOUCHEL (Jean-Marie)</AU>
  <AF>Centre de Recherche Public-Gabriel Lippmann, CREBS, 162a, Avenue de la Faïencerie/1511 Luxembourg/Luxembourg (1 aut., 2 aut.); Fondation Universitaire Luxembourgeoise, 185, avenue de Longwy/6700 Arlon/Belgique (1 aut., 3 aut.); Université de Metz, Centre d'Etudes Géographiques, Ile du Saulcy/57405 Metz/France (4 aut.); Université de Liège, Institut de Botanique (B.22), Sart Tilman/4000 Liège/Belgique (5 aut.); UMR Sisyphe 7619 CNRS/UPMC, 4 Place Jussieu/75005 Paris/France (1 aut.); CEREVE, Ecole Nationale des Ponts et Chaussées, 6 &amp; 8 av. Blaise Pascal, Cité Descartes/77455 Marne-la-Vallée/France (2 aut.)</AF>
  <DT>Publication en série; Congrès; Niveau analytique</DT>
  <SO>Hydrobiologia : (The Hague); ISSN 0018-8158; Coden HYDRB8; Pays-Bas; Da. 1999;  Vol. 410; Pp. 97-102; Bibl. 21 ref.</SO>
  <LA>Anglais</LA>
  <EA>The snapshot' sampling methodology was applied to the spatial analysis of phosphorus and nitrogen concentrations and fluxes in the transnational upper Sûre watershed (Belgium-Luxembourg) during stable low discharge summer periods in 1991 and 1992. The results show clear differences in nitrogen concentrations and specific loads between agricultural and forested sub-basins, whereas for phosphorus the dependence on land use is less evident. The simultaneous measurement of stream discharge and nutrient concentrations permitted a quantitative evaluation of the input from point respectively diffuse sources and loads from the tributaries as well as the retention capacity by self-purification or sedimentation of the different phosphorus and nitrogen forms in the various sections of the Sûre river. The results illustrate the utility of the snapshot' sampling as an important tool for an integrated watershed management.</EA>
  <CC>002A14A02; 002A14D02C</CC>
  <FD>Echantillonnage; Technique; Variation spatiale; Concentration; Azote; Phosphore; Flux; Nutriment; Eutrophisation; Hydrodynamique; Cours eau; Gestion intégrée; Bassin versant; Belgique; Luxembourg</FD>
  <FG>Europe; Milieu eau douce; Méthodologie</FG>
  <ED>Sampling; Technique; Spatial variation; Concentration; Nitrogen; Phosphorus; Flux; Nutrient; Eutrophication; Hydrodynamics; Stream; Integrated management; Watershed; Belgium; Luxembourg</ED>
  <EG>Europe; Freshwater environment; Methodology</EG>
  <SD>Muestreo; Técnica; Variación espacial; Concentración; Nitrógeno; Fósforo; Flujo; Nutriente; Eutrofización; Hidrodinámica; Curso agua; Gestión integrada; Cuenca; Belgica; Luxemburgo</SD>
  <LO>INIST-5329.354000081914300110</LO>
  <ID>00-0205064</ID>
</server>
<server>
  <NO>: PASCAL 02-0188058 INIST</NO>
  <ET>Control of the eutrophication of the reservoir of Esch-sur-Sûre (Luxembourg): evaluation of the phosphorus removal by predams</ET>
  <AU>SALVIA-CASTELLVI (M.); DOHET (A.); BORGHT (P. Vander); HOFFMANN (L.)</AU>
  <AF>Centre de Recherche Public-Gabriel Lippmann, Cellule de Recherche en Environnement et Biotechnologies, 162a avenue de la Faïencerie/1511 Luxembourg/Luxembourg (1 aut., 2 aut., 4 aut.); Fondation Universitaire de Luxembourg, 185 avenue de Longwy/6700 Arlon/Belgique (1 aut., 3 aut.)</AF>
  <DT>Publication en série; Niveau analytique</DT>
  <SO>Hydrobiologia : (The Hague); ISSN 0018-8158; Coden HYDRB8; Pays-Bas; Da. 2001;  Vol. 459; Pp. 61-71; Bibl. 1 p.1/4</SO>
  <LA>Anglais</LA>
  <EA>The phosphorus retention capacity was established for two predams having the same water supply and the same seasonality but with contrasting hydraulic retention times and phosphorus loads. The annual retention of total phosphorus of the shallow Misère predam amounted to about 60%, whereas the deeper Bavigne predam retained about 82%; for soluble reactive phosphorus (SRP) the annual retention rates were 4 and 54%, respectively. The different behaviour of the predams is probably due to their different flow regimes and morphology. The highest retention rates were observed during summer, when up to 90% of SRP could be retained in the Bavigne predam. The comparison of the measured removal rates of SRP with those calculated on the basis of the model proposed by Benndorf &amp; Pütz (Wat. Res. 1987 21: 829-838) shows a rather good agreement for the thermally stratified Bavigne predam. For the shallow Misère predam, the model adequately predicts the annual trends of SRP removal, but a great discrepancy is observed for the absolute values. This is probably due to the phytoplankton composition and to the release of phosphorus from the sediments in the summer period.</EA>
  <CC>001D16A04C</CC>
  <FD>Eutrophisation; Phosphore; Rétention; Barrage; Lutte antipollution; Phytoplancton; Plancton; Variation saisonnière; Variation spatiale; Lac artificiel; Luxembourg</FD>
  <FG>Europe; Milieu eau douce; Pollution eau; Facteur anthropique</FG>
  <ED>Eutrophication; Phosphorus; Retention; Dam; Pollution control; Phytoplankton; Plankton; Seasonal variation; Spatial variation; Artificial lake; Luxembourg</ED>
  <EG>Europe; Freshwater environment; Water pollution; Anthropogenic factor</EG>
  <SD>Eutrofización; Fósforo; Retención; Presa; Lucha anticontaminación; Fitoplancton; Plancton; Variación estacional; Variación espacial; Lago artificial; Luxemburgo</SD>
  <LO>INIST-5329.354000103467410080</LO>
  <ID>02-0188058</ID>
</server>
<server>
  <NO>: PASCAL 04-0564551 INIST</NO>
  <ET>Vancomycin and ciprofloxacin: Systemic antibiotic administration for peritoneal dialysis-associated peritonitis</ET>
  <AU>GOFFIN (Eric); HERBIET (Lawrence); POUTHIER (Dominique); POCHET (Jean-Michel); LAFONTAINE (Jean-Jacques); CHRISTOPHE (Jean-Louis); GIGI (Jacques); VANDERCAM (Bernard)</AU>
  <AF>Department of Nephrology, Cliniques Universitaires St. Luc, Université Catholique de Louvain/Brussels/Belgique (1 aut., 2 aut.); Department of Nephrology, Centre Hospitalier/Luxembourg (3 aut.); Clinique Ste. Elisabeth/Namur/Belgique (4 aut.); Hôpital St. Joseph/Arlon/Belgique (5 aut.); Hôpital St. Joseph/Gilly/Belgique (6 aut.); Department of Microbiology, Cliniques Universitaires St. Luc, Université Catholique de Louvain/Brussels/Belgique (7 aut.); Department of Internal Medicine, Cliniques Universitaires St. Luc, Université Catholique de Louvain/Brussels/Belgique (8 aut.)</AF>
  <DT>Publication en série; Niveau analytique</DT>
  <SO>Peritoneal dialysis international; ISSN 0896-8608; Canada; Da. 2004; Vol. 24; No. 5; Pp. 433-439; Bibl. 35 ref.</SO>
  <LA>Anglais</LA>
  <EA>✦ Objectives: Peritonitis due to peritoneal dialysis (PD) is best treated empirically while waiting for the results of the dialysate culture. Thus, antibiotic therapy must cover both gram-positive and gram-negative micro-organisms. First, over a period of 9 years in a multicenter study we evaluated the efficiency of a vancomycin and ciprofloxacin combination given as the first-line treatment protocol for PD peritonitis. Second, we evaluated whether a systemic route of administration of the antibiotics could be an interesting alternative to the usual cumbersome intraperitoneal drug administration. ✦ Methods: Vancomycin 15 mg/kg body weight, intravenous, and oral ciprofloxacin 250 mg two times per day (500 mg twice per day if residual creatinine clearance was above 3 mUminute) were prescribed at diagnosis of peritonitis. Vancomycin injections were repeated (when blood trough level was expected to be below 12 μg/mL) in cases of gram-positive organisms for a total duration of 3 weeks. Ciprofloxacin was given for a total of 3 weeks in cases of gram-negative and a total of 10 days for susceptible gram-positive infections. ✦ Results: A total of 129 episodes of peritonitis occurred; 28 of them were not included in the study because of protocol violation (n = 15) or fungal (n = 7) or fecal (n = 6) peritonitis, leaving 101 peritonitis episodes for analysis. 52 (51.5%) gram-positive and 28 (27.7%) gram-negative organisms were grown; 38 gram-positive organisms were coagulase-negative staphylococci. No organism was identified in 8 peritonitis episodes, whereas 13 peritonitis episodes were caused by more than 1 organism. 35% of the coagulase-negative staphylococci were resistant to first-generation cephalosporin and methicillin, whereas all were susceptible to vancomycin. For gram-negative bacilli, the susceptibility rate was 96% and 95% for ciprofloxacin and ceftazidime respectively. The overall treatment success rate was 77.2% (78 of the 101 peritonitis episodes): 61.4% at first intention and 15.8% after optimization of the antibiotic therapy (second intention). The protocol failed in 22.8% of the peritonitis episodes. Hospitalization was required in 52% of the peritonitis episodes; average hospitalization was 11 (range 1- 45) days. ✦ Conclusion: Systemic vancomycin and ciprofloxacin administration is a simple and efficient first-line protocol antibiotic therapy for PD peritonitis. In our opinion, vancomycin should still be used for gram-positive infections because of its high susceptibility rate compared with first-generation cephalosporins, providing a close monitoring of the local epidemiology. Oral ciprofloxacin provides satisfactory results in gram-negative infections, comparable to those obtained with intraperitoneal ceftazidime or aminoglycosides.</EA>
  <CC>002B27B03; 002B25H; 002B14A01</CC>
  <FD>Insuffisance rénale; Dialyse péritonéale; Epuration extrarénale; Péritonite; Vancomycine; Ciprofloxacine; Antibiotique; Staphylococcus aureus; Rifampicine; Mupirocine; Antibactérien; Antituberculeux</FD>
  <FG>Micrococcaceae; Micrococcales; Bactérie; Appareil urinaire pathologie; Rein pathologie; Glycopeptide; Peptide; Polypeptide; Fluoroquinolone dérivé; Quinolone dérivé; Abdomen pathologie</FG>
  <ED>Renal failure; Peritoneal dialysis; Extrarenal dialysis; Peritonitis; Vancomycin; Ciprofloxacin; Antibiotic; Staphylococcus aureus; Rifampicin; Mupirocin; Antibacterial agent; Antituberculous agent</ED>
  <EG>Micrococcaceae; Micrococcales; Bacteria; Urinary system disease; Kidney disease; Glycopeptide; Peptides; Polypeptide; Fluoroquinolone derivatives; Quinolone derivatives; Abdominal disease</EG>
  <SD>Insuficiencia renal; Diálisis peritoneal; Depuración extrarrenal; Peritonitis; Vancomicina; Ciprofloxacino; Antibiótico; Staphylococcus aureus; Rifampicina; Mupirocina; Antibacteriano; Antituberculoso</SD>
  <LO>INIST-21280.354000122361140020</LO>
  <ID>04-0564551</ID>
</server>
<server>
  <NO>: PASCAL 05-0340526 INIST</NO>
  <ET>Dissolved and particulate nutrient export from rural catchments : A case study from Luxembourg</ET>
  <AU>SALVIA-CASTELLVI (Mercè); IFFLY (Jean Francois); VANDER BORGHT (Paul); HOFFMANN (Lucien); HAYGARTH (P. M.)</AU>
  <AF>CRF-Gabriel Lippmann, 162A, av. de la Faiencerie, Grand-duchy of Luxembourg/1511 Luxembourg/Luxembourg (1 aut., 2 aut., 4 aut.); Fondation Universitaire Luxembourgeoise, 185, av. de Longwy/6700 Arlon/Belgique (1 aut., 3 aut.); Institute of Grassland and Environmental Research (IGER), North Wyke Research Station/Okehampton, Devon EX20 2SB/Royaume-Uni (1 aut.)</AF>
  <DT>Publication en série; Niveau analytique</DT>
  <SO>Science of the total environment; ISSN 0048-9697; Coden STENDL; Irlande; Da. 2005;  Vol. 344; No. 1-3; Pp. 51-65; Bibl. 1 p.1/4</SO>
  <LA>Anglais</LA>
  <EA>Nutrient enrichment of freshwaters continues to be one of the most serious problems facing the management of surface waters. Effective remediation/conservation measures require accurate qualitative and quantitative knowledge of nutrient sources, transport mechanisms, transformations and annual dynamics of different nitrogen (N) and phosphorus (P) forms. In this paper, nitrate (NO<sub>3</sub>-N), soluble reactive phosphorus (SRP) and total phosphorus (TP) concentrations and loads are presented for two adjacent rural basins of 306 km<sup>2</sup>and 424 km<sup>2</sup>, and for five sub-basins differing in size (between 1 km<sup>2</sup>and 33 km<sup>2</sup>), land use (extent of forest cover between 20% and 93%) and household pressure (from 0 to 40 people/km<sup>2</sup>) with the aim of studying the influence of land use and catchment size on nutrient exports. The studied catchments are all situated on Devonian schistous substrates in the Ardennes region (Belgium-Luxembourg), and therefore have similar hydrological regimes. As the study period could not be the same for all basins, annual export coefficients were corrected with the 25 years normalized discharge of the Sûre River: two regression analyses (for dry and humid periods) relating monthly nutrient loads to monthly runoff were used to determine correction factors to be applied to each parameter and each basin. This procedure allows for the comparing annual export coefficients from basins sampled in different years. Results show a marked seasonal response and a large variability of NO<sub>3</sub>-N export loads between forested (4 kg N ha<sup>-1</sup>year<sup>-1</sup>), agricultural (27-33 kg N ha<sup>-1</sup>year<sup>-1</sup>) and mixed catchments (17-22 kg N ha<sup>-1</sup>year<sup>-1</sup>). For SRP and TP, no significant agricultural impact was found. Land and bank erosion control the total P massflow in the studied catchments (0.4-1.3 kg P ha<sup>-1</sup>year<sup>-1</sup>), which is mostly in a particulate form, detached and transported during storm events. Soluble reactive P fluxes ranged between 10% and 30% of the TP mass, depending on the importance of point sources in the basins studied. No relation was found between the size of the basins and the export of nitrate, SRP or TP. Nutrient export, specially for NO<sub>3</sub>-N and TP, shows significant inter-annual variations, closely linked to inter-annual discharge variations. Flow and load frequency data analysis confirm this association for all the basins on an annual basis. Seasonal or storm specific fluxes strongly deviate from their annual values.</EA>
  <CC>001D16A04C; 001E01O04; 002A32B06; 226B04</CC>
  <FD>Zone rurale; Bassin versant; Eau surface; Pollution eau; Nutriment; Azote; Phosphore; Matière dissoute; Particule en suspension; Perte substance; Distribution concentration; Variation saisonnière; Variation interannuelle; Variation spatiale; Occupation sol; Densité population; Protection environnement; Prévention pollution; Lutte antipollution; Cours eau; Eutrophisation; Luxembourg; Ardennes; Belgique</FD>
  <FG>Europe; Champagne Ardenne; France</FG>
  <ED>Rural area; Watershed; Surface water; Water pollution; Nutrient; Nitrogen; Phosphorus; Dissolved matter; Suspended particle; Substance loss; Concentration distribution; Seasonal variation; Interannual variation; Spatial variation; Land use; Population density; Environmental protection; Pollution prevention; Pollution control; Stream; Eutrophication; Luxembourg; Ardennes; Belgium</ED>
  <EG>Europe; Champagne-Ardenne; France</EG>
  <SD>Zona rural; Cuenca; Agua superficie; Contaminación agua; Nutriente; Nitrógeno; Fósforo; Materia disuelta; Partícula en suspensión; Pérdida sustancia; Distribución concentración; Variación estacional; Variación interanual; Variación espacial; Ocupación terreno; Densidad población; Protección medio ambiente; Prevención polución; Lucha anticontaminación; Curso agua; Eutrofización; Luxemburgo; Ardennes; Belgica</SD>
  <LO>INIST-15662.354000124704240050</LO>
  <ID>05-0340526</ID>
</server>
<server>
  <NO>: PASCAL 09-0120508 INIST</NO>
  <ET>Long-Term Benefit of High-Dose Epirubicin in Adjuvant Chemotherapy for Node-Positive Breast Cancer : 15-Year Efficacy Results of the Belgian Multicentre Study</ET>
  <AU>DEAZAMBUJA (Evandro); PAESMANS (Marianne); BEAUDUIN (Marc); VINDEVOGHEL (Anita); CORNEZ (Nathalie); FINET (Claude); RIES (Fernand); CLOSON-DEJARDIN (Marie Thérèse); KERGER (Joseph); GOBERT (Philippe); FOCAN (Christian); TAGNON (Alain); DOLCI (Stella); NOGARET (Jean M.); DI LEO (Angela); PICCART-GEBHART (Martine J.)</AU>
  <AF>Institut Jules Bordet and Université Libre de Bruxelles/Brussels/Belgique; Hopital de Jolimont-Lobbes/Belgique; Centre Hospitalier Universitaire de Tivoli/La Louvière/Belgique; Clinique Sainte Elisabeth/Namur/Belgique; Hôpital de Braine L'Alleud/Waterloo/Belgique; Centre Hospitalier Universitaire de Liège/France; Centre Hospitalier Chrétien/Liège/Belgique; Service d'Oncologie, Cliniques Universitaires Université Catholique de Louvain/Godinne/Belgique; Clinique Saint-Joseph/Arlon/Belgique; Réseau Hospitalier de Médecine Sociale/Tournai/Belgique; Programa de Pós-graduação em Medicina: Ciências Médicas, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul/Porto Alegre/Brésil; Centre Hospitalier de Luxembourg/Luxembourg; Hospital of Prato/Prato/Italie</AF>
  <DT>Publication en série; Niveau analytique</DT>
  <SO>Journal of clinical oncology; ISSN 0732-183X; Etats-Unis; Da. 2009; Vol. 27; No. 5; Pp. 720-725; Bibl. 22 ref.</SO>
  <LA>Anglais</LA>
  <EA>Purpose The 4-year results of this trial demonstrated that a higher dose of epirubicin with cyclophosphamide (HEC) is superior to a lower dose of epirubicin, 60 mg/m<sup>2</sup>(EC), for event-free survival (EFS; 27% reduction), but is not superior to classical oral cyclophosphamide, methotrexate, and fluorouracil (CMF) in the adjuvant treatment of node-positive breast cancer. Herein we report the 15-year data on efficacy and long-term toxicity of this three-arm Belgian multi-center trial. Patients and Methods Between March 1988 and December 1996, 777 eligible patients were randomly assigned to six cycles of CMF, eight cycles of EC, or eight cycles HEC. Results The 15-year EFS was 45% for patients who received CMF, 39% for patients who received EC, and 50% for patients who received HEC. The hazard ratios (HR) were 0.77 for HEC versus EC (95% Cl, 0.60 to 0.98; P = .03), 0.90 for HEC versus CMF (P = .39), and 0.86 for EC versus CMF (P = .21). No difference in overall survival (OS) was seen. Cardiac toxicity was more frequent with HEC than with CMF (11 patients v 1 patient; P = .006), but no more than with EC (P = .21). Conclusion Treatment with HEC demonstrated superior EFS when compared with lower-dose epirubicin. However, we do not recommend the use of HEC regimen in daily clinical practice, mainly because of the higher risk of cardiotoxicity related to the cumulative doses of epirubicin and the lack of superiority of anthracyclines over CMF in our study.</EA>
  <CC>002B04; 002B20E02</CC>
  <FD>Epirubicine; Long terme; Dose forte; Cancer du sein; Traitement adjuvant; Efficacité traitement; Chimiothérapie; Belgique; Cancérologie; Anticancéreux</FD>
  <FG>Traitement; Europe; Anthracyclines; Tumeur maligne; Cancer; Pathologie de la glande mammaire; Pathologie du sein</FG>
  <ED>Epirubicin; Long term; High dose; Breast cancer; Adjuvant treatment; Treatment efficiency; Chemotherapy; Belgium; Cancerology; Antineoplastic agent</ED>
  <EG>Treatment; Europe; Anthracyclins; Malignant tumor; Cancer; Mammary gland diseases; Breast disease</EG>
  <SD>Epirubicina; Largo plazo; Dosis fuerte; Cáncer del pecho; Tratamiento adyuvante; Eficacia tratamiento; Quimioterapia; Belgica; Cancerología; Anticanceroso</SD>
  <LO>INIST-20094.354000185427620120</LO>
  <ID>09-0120508</ID>
</server>
<server>
  <NO>: PASCAL 09-0280655 INIST</NO>
  <ET>Assessment of determinants for osteoporosis in elderly men</ET>
  <AU>SCHOLTISSEN (S.); GUILLEMIN (F.); BRUYERE (O.); COLLETTE (J.); DOUSSET (B.); KEMMER (C.); CULOT (S.); CREMER (D.); DEJARDIN (H.); HUBERMONT (G.); LEFEBVRE (D.); PASCAL-VIGNERON (V.); WERYHA (G.); REGINSTER (J. Y.)</AU>
  <AF>Department of Public Health, Epidemiology and Health Economics, University of Liège, Avenue de l'Hôpital 3-CHU B23/4000 Sart-Tilman/Belgique (1 aut., 3 aut., 14 aut.); EA 4003 &amp; Inserm CIC-EC &amp; CHU de Nancy, Nancy University, BP 184/54505 Vandoeuvre-lès-Nancy/France (2 aut.); Service d'Endocrinologie, CHU de Nancy, Rue du Morvan 5/54500 Vandoeuvre/France (12 aut., 13 aut.); Bone &amp; Cartilage Markers Laboratory, CHU-Department of Clinical Biology, University of Liège/4000 Sart-Tilman/Belgique (4 aut.); Laboratoire de Biochimie et Biologie Moléculaire, Hôpital Central, Avenue du Maréchal de Lattre de Tassigny 19/54000 Nancy/France (5 aut.); Association Luxembourgeoise pour l'Etude du Métabolisme Osseux, Boulevard J-F Kennedy 1/4170 Esch/Alzette/Luxembourg (6 aut.); Observatoire de la Santé, Province de Luxembourg, Rue de la Station 49/6900 Marloie/Belgique (7 aut.); Hôpital du Centre Ardenne de Libramont (CHA), Avenue de Houffalize 35/6800 Libramont/Belgique (8 aut.); Hôpital Princesse Paola (IFAC), Rue du Viviers 21/6900 Marche-en-Famenne/Belgique (9 aut.); Hôpital Sainte-Thérèse (IFAC), Chaussée de Houffalize 1/6600 Bastogne/Belgique (10 aut.); Clinique Saint-Joseph (CSL), Rue des Déportés 137/6700 Arlon/Belgique (11 aut.)</AF>
  <DT>Publication en série; Niveau analytique</DT>
  <SO>Osteoporosis international; ISSN 0937-941X; Royaume-Uni; Da. 2009; Vol. 20; No. 7; Pp. 1157-1166; Bibl. 41 ref.</SO>
  <LA>Anglais</LA>
  <EA>Summary The aim of this cross-sectional study was to determine and quantify some determinants associated to low bone mineral density (BMD) in elderly men. This study showed that ageing, a lower body mass index (BMI), a higher blood level of C-terminal cross-linking telopeptides of type I collagen (CTX-1), family history of osteoporosis, and/or fracture and prior fracture were associated with bone mineral density. Introduction Our aims were to identify some determinants associated to low bone mineral density in men and to develop a simple algorithm to predict osteoporosis. Methods A sample of 1,004 men aged 60 years and older was recruited. Biometrical, serological, clinical, and life-style determinants were collected. Univariate, multivariate, and logistic regression analyses were performed. Receiver operating characteristic analysis was used to assess the discriminant performance of the algorithm. Results In the multiple regression analysis, only age, BMI, CTX-1, and family history of osteoporosis and/or fracture were able to predict the femoral neck T-score. When running the procedure with the total hip T-score, prior fracture also appeared to be significant. With the lumbar spine T-score, only age, BMI, and CTX-1 were retained. The best algorithm was based on age, BMI, family history, and CTX-1. A cut-off point of 0.25 yielded a sensibility of 78%, a specificity of 59% with an area under the curve of 0.73 in the development and validation cohorts. Conclusion Ageing, a lower BMI, higher CTX-1, family history, and prior fracture were associated with T-score. Our algorithm is a simple approach to identify men at risk for osteoporosis.</EA>
  <CC>002B15A</CC>
  <FD>Ostéoporose; Personne âgée; Epidémiologie; Rhumatologie; Ostéodensitométrie</FD>
  <FG>Homme; Pathologie du système ostéoarticulaire</FG>
  <ED>Osteoporosis; Elderly; Epidemiology; Rheumatology; Osteodensitometry</ED>
  <EG>Human; Diseases of the osteoarticular system</EG>
  <SD>Osteoporosis; Anciano; Epidemiología; Reumatología; Osteodensitometría</SD>
  <LO>INIST-22974.354000188561390070</LO>
  <ID>09-0280655</ID>
</server>
<server>
  <NO>: PASCAL 09-0414377 INIST</NO>
  <ET>Assessing the Accuracy of Simulation Model for Septoria Leaf Blotch Disease Progress on Winter Wheat</ET>
  <AU>EL JARROUDI (M.); DELFOSSE (P.); MARAITE (H.); HOFFMANN (L.); TYCHON (B.)</AU>
  <AF>Université de Liège, 185 Avenue de Longwy/6700 Arlon/Belgique (1 aut., 5 aut.); Centre de Recherche Public - Gabriel Lippmann, Département Environnement et Agro-biotechnologies (EVA), 41, Rue du Brill/4422 Belvaux/Luxembourg (2 aut., 4 aut.); Unité de Phytopathologie, Université catholique de Louvain (UCL), Croix du Sud 2/3/1348 Louvain-la-Neuve/Belgique (3 aut.)</AF>
  <DT>Publication en série; Niveau analytique</DT>
  <SO>Plant disease; ISSN 0191-2917; Coden PLDIDE; Etats-Unis; Da. 2009; Vol. 93; No. 10; Pp. 983-992; Bibl. 45 ref.</SO>
  <LA>Anglais</LA>
  <EA>A mechanistic model, PROCULTURE, for assessing the development of each of the last five leaf layers and the progress of Septoria leaf blotch, caused by Septoria tritici (teleomorph Mycosphaerella graminicola), has been applied on susceptible and weakly susceptible winter wheat (Triticum aestivum) cultivars in two locations (Everlange and Reuland) in Luxembourg over a 3-year period (2000 to 2002). A double performance assessment of PROCULTURE was conducted in this study. First, the capability of PROCULTURE to correctly simulate S. tritici incidence was checked. Second, the model's ability to accurately estimate disease severity was assessed on the basis of the difference between simulated and observed levels of disease development at each leaf layer. The model accurately predicted disease occurrence in the 2000 and 2002 seasons, on susceptible and semi-susceptible cultivars, with a probability of detection (POD) exceeding 0.90. However, in 2001, even though the POD never fell below 0.90, the false alarm ratio (FAR) was too high to consider the simulations satisfactory. Concerning the evaluation of disease severity modeling, statistical tests revealed accurate simulations performed by PROCULTURE for susceptible cultivars in 2000 and 2002. By contrast, for weakly susceptible cultivars, the model overestimated disease severity, especially for the upper leaves, for the same period.</EA>
  <CC>002A34G</CC>
  <FD>Triticum aestivum; Simulation; Modèle; Septoria; Microbiologie; Phytopathologie; Phytopathogène</FD>
  <FG>Gramineae; Monocotyledones; Angiospermae; Spermatophyta; Fungi Imperfecti; Fungi; Plante céréalière</FG>
  <ED>Triticum aestivum; Simulation; Models; Septoria; Microbiology; Plant pathology; Plant pathogen</ED>
  <EG>Gramineae; Monocotyledones; Angiospermae; Spermatophyta; Fungi Imperfecti; Fungi; Cereal crop</EG>
  <SD>Triticum aestivum; Simulación; Modelo; Septoria; Microbiología; Fitopatología; Fitopatógeno</SD>
  <LO>INIST-12673.354000171098370020</LO>
  <ID>09-0414377</ID>
</server>
<server>
  <NO>: PASCAL 10-0128388 INIST</NO>
  <FT>Fusarioses sur blé d'hiver au Grand-Duché de Luxembourg: Premiers résultats d'une enquête commencée en 2007 sur l'identification des agents de la fusariose : Céréales</FT>
  <ET>(WINTER WHEAT, FUSARIUM AND MYCOTOXINS IN LUXEMBOURG)</ET>
  <AU>GIRAUD (Frédéric); PASQUALI (M.); VRANCKEN (C.); COCCO (E.); MUNAUT (F.); EL JARROUDI (M.); BOHN (T.); HOFFMANN (L.); DELFOSSE (P.)</AU>
  <AF>Département Environnement et Agro-biotechnologies (EVA), CRP-Gabriel Lippmann/4422 Belvaux/Luxembourg (1 aut., 2 aut., 3 aut., 4 aut., 7 aut., 8 aut., 9 aut.); BCCM-MUCL, Université catholique de Louvain/1348 Louvain-la-Neuve/Belgique (5 aut.); Département Sciences et Gestion de l'Environnement, Université de Liège/6700 Arlon/Belgique (6 aut.)</AF>
  <DT>Publication en série; Niveau analytique</DT>
  <SO>Phytoma, la défense des végétaux; ISSN 1164-6993; France; Da. 2009; No. 622-23; Pp. 29-32; Abs. anglais</SO>
  <LA>Français</LA>
  <FA>Au Grand-Duché de Luxembourg, la campagne 2006-2007 a été caractérisée par un hiver relativement doux et un printemps pluvieux. Ces conditions météorologiques ont permis le développement de nombreuses maladies cryptogamiques sur le blé d'hiver, dont la fusariose. Cette maladie a été suivie sur 17 sites couvrant le G-D de Luxembourg par des mesures de prévalence (pourcentage moyen d'épis visuellement infectés) et de sévérité (pourcentage moyen d'épillets atteints par épi). Des valeurs moyennes de 8,5±15,5 % pour la prévalence et de 21,0 ± 17,8 % pour la sévérité ont été enregistrées avec des différences significatives entre les cantons nord et sud pour la sévérité. Plus de 600 souches isolées des 17 sites ont été identifiées suivant des critères morphologiques et l'emploi d'outils moléculaires. 5 espèces semblent associées à la fusariose: Fusarium graminearum (30%), F. culmorum (11%), F. poae (19,4 %) (3 espèces potentiellement productrices de mycotoxines), F avenaceum (21 %) et Microdochium nivale (17 %). Cette étude est la première du genre à avoir été faite au Grand-Duché de Luxembourg.</FA>
  <CC>002A34G; 002A32</CC>
  <FD>Mycose; Résultat; Enquête; 2007; Identification; Mycotoxine; Phytopathologie; Triticum aestivum; Fusarium; Blé; Luxembourg; Plante en C3; Culture d'hiver</FD>
  <FG>Infection; Toxine; Gramineae; Monocotyledones; Angiospermae; Spermatophyta; Fungi Imperfecti; Fungi; Céréale; Europe; Plante céréalière; Type C3; Végétal; Europe Ouest; Zone tempérée</FG>
  <ED>Mycosis; Result; Survey; 2007; Identification; Mycotoxin; Plant pathology; Triticum aestivum; Fusarium; Wheat; Luxembourg; Winter crops</ED>
  <EG>Infection; Toxin; Gramineae; Monocotyledones; Angiospermae; Spermatophyta; Fungi Imperfecti; Fungi; Cereal; Europe; Cereal crop; C3-Type; Vegetals; Western Europe; Temperate zone</EG>
  <SD>Micosis; Resultado; Encuesta; 2007; Identificación; Micotoxina; Fitopatología; Triticum aestivum; Fusarium; Trigo; Luxemburgo; Cultivos de invierno</SD>
  <LO>INIST-2482.354000190034000060</LO>
  <ID>10-0128388</ID>
</server>
<server>
  <NO>: PASCAL 10-0308293 INIST</NO>
  <ET>Fusarium head blight and associated mycotoxin occurrence on winter wheat in Luxembourg in 2007/2008</ET>
  <AU>GIRAUD (Frédéric); PASQUALI (Matias); EL JARROUDI (Moussa); VRANCKEN (Carine); BROCHOT (Céline); COCCO (Emmanuelle); HOFFMANN (Lucien); DELFOSSE (Philippe); BOHN (Torsten)</AU>
  <AF>Department of the Environment and Agro-Biotechnologies, CRP-Gabriel Lippmann, 41, rue du Brill/4422 Belvaux/Luxembourg (1 aut., 2 aut., 4 aut., 5 aut., 6 aut., 7 aut., 8 aut., 9 aut.); Départment de Sciences et Gestion de l'Environnement, Université de Liège/6700 Arlon/Belgique (3 aut.)</AF>
  <DT>Publication en série; Niveau analytique</DT>
  <SO>Food additives &amp; contaminants : part A chemistry, analysis, control, exposure &amp; risk assessment; Royaume-Uni; Da. 2010;  Vol. 27; No. 6; Pp. 825-835; Bibl. 1 p.3/4</SO>
  <LA>Anglais</LA>
  <EA>Fusarium head blight (FHB) is among the major causes of reduced quality in winter wheat and its products. In addition, the causal fungi produce a variety of toxins. A relatively high FHB infection rate in winter wheat was observed in 2007 and 2008 in Luxembourg. A fusariotoxin survey was carried out in 17 different geographical locations. Three groups of Fusarium mycotoxins (trichothecenes A and B and zearalenone) were analysed by a multi-detection HPLC-MS/MS method. Fusarium strains were also investigated by morphological and molecular methods. In addition, questionnaires relating to cultural practices were sent to the farmers managing the 17 fields investigated. FHB prevalence ranged from 0.3 to 65.8% (mean: 8.5%) in 2007 and from 0 to 24.5% (mean: 8.3%) in 2008. Results of morphological and molecular identification showed that the most common species isolated from diseased wheat spikes was F. graminearum (33.1%), followed by F. avenaceum (20.3%) and F. poae (17.8%). The chemical analysis revealed that 75% of the investigated fields were contaminated by deoxynivalenol (DON, range 0-8111μg/kg). The preceding crop was highly and significantly correlated to the number of grains infected and had a significant impact on disease prevalence (p=0.025 and 0.017, respectively, Fisher's F-test). A trend was found for maize as the preceding crop (p=0.084, Tukey's test) to predict the amount of DON in the fields. This is the first report on the occurrence of DON and ZON in naturally infected wheat grains sampled from Luxembourg.</EA>
  <CC>002A35E; 002A35B03</CC>
  <FD>Fusarium; Tête; Mycotoxine; Surveillance; Blé; Chromatographie phase liquide; Biologie moléculaire; Réaction chaîne polymérase; Trichothécène; Zéaralénone</FD>
  <FG>Fungi Imperfecti; Fungi; Toxine; Céréale</FG>
  <ED>Fusarium; Head; Mycotoxin; Surveillance; Wheat; Liquid chromatography; Molecular biology; Polymerase chain reaction; Trichothecene; Zearalenone</ED>
  <EG>Fungi Imperfecti; Fungi; Toxin; Cereal</EG>
  <SD>Fusarium; Cabeza; Micotoxina; Vigilancia; Trigo; Cromatografía fase líquida; Biología molecular; Reacción cadena polimerasa; Tricoteceno; Zearalenona</SD>
  <LO>INIST-20834A.354000170471020090</LO>
  <ID>10-0308293</ID>
</server>
<server>
  <NO>: PASCAL 10-0391942 INIST</NO>
  <ET>Measuring soil organic carbon in croplands at regional scale using airborne imaging spectroscopy</ET>
  <AU>STEVENS (Antoine); UDELHOVEN (Thomas); DENIS (Antoine); TYCHON (Bernard); LIOY (Rocco); HOFFMANN (Lucien); VAN WESEMAEL (Bas); GUERRERO (César); VISCARRA ROSSEL (Raphael A.); MOUAZEN (Abdul Mounem)</AU>
  <AF>Department of Geography, Université catholique de Louvain, 3 place Pasteur/1348 Louvain-La-Neuve/Belgique (1 aut., 7 aut.); Departement Environment and Agro-biotechnologies, Centre de Recherche Public-Gabriel Lippmann, 41 rue du Brill/4422 Belvaux/Luxembourg (2 aut., 6 aut.); Department of Environmental Sciences and Management, University of Liege, Campus of Arlon, 185 avenue de Longwy/6700 Arlon/Belgique (3 aut., 4 aut.); CONVIS Herdbuch Service Élevage et Génétique-Société coopérative, B.P. 313/9004 Ettelbruck/Luxembourg (5 aut.); Department of Agrochemistry and Environment, University Miguel Hernández, Avenida de la Universidad s/n/Elche, Alicante 3202/Espagne (1 aut.); CSIRO Land and Water, Bruce E. Butler Laboratory, GPO Box 1666/Canberra, ACT 2601/Australie (2 aut.); National Soil Resources Institute, Natural Resources Department, Cranfield University/Cranfield, Bedfordshire, MK43 0AL/Royaume-Uni (3 aut.)</AF>
  <DT>Publication en série; Papier de recherche; Niveau analytique</DT>
  <SO>Geoderma : (Amsterdam); ISSN 0016-7061; Coden GEDMAB; Pays-Bas; Da. 2010;  Vol. 158; No. 1-2; Pp. 32-45; Bibl. 3/4 p.</SO>
  <LA>Anglais</LA>
  <EA>Conventional sampling techniques are often too expensive and time consuming to meet the amount of data required in soil monitoring or modelling studies. The emergence of portable and flexible spectrometers could provide the large amount of spatial data needed. In particular, the ability of airborne imaging spectroscopy to cover large surfaces in a single campaign and to study the spatial distribution of soil properties with a high spatial resolution represents an opportunity for improving the monitoring of soil characteristics and soil threats such as the decline of soil organic matter in the topsoil. However, airborne imaging spectroscopy has been generally applied over small areas with homogeneous soil types and surface conditions. Here, five hyperspectral images acquired with the AHS-160 sensor (430 nm-2540 nm) were analysed with the objective to map soil organic carbon (SOC) at a regional scale. The study area, covering a surface of ∼420 km<sup>2</sup>and located in Luxembourg, is characterized by different soil types and a high variation in SOC contents. Reflectance data were related to surface SOC contents of bare croplands by means of 3 different multivariate calibration techniques: partial least square regression (PLSR), penalized-spline signal regression (PSR) and support vector machine regression (SVMR). The performance of these statistical tools was tested under different combinations of calibration/validation sets (global and local calibrations stratified according to agro-geological zones, soil type and image number). Under global calibration, the Root Mean Square Error in the Predictions reached 5.3-6.2 g C kg<sup>-1</sup>. Under local calibrations, this error was reduced by a factor up to 1.9. SOC maps of bare agricultural fields were produced using the best calibration model. Two map excerpts were shown, which display intra- and inter-field variability of SOC contents possibly related to topography and land management.</EA>
  <CC>002A32; 001E01P03; 001E01M04; 226C03; 225B04</CC>
  <FD>Carbone organique; Sol agricole; Champ cultivé; Télédétection; Méthode aéroportée; Capteur imagerie hyperspectral; Pouvoir réflecteur; Spectrométrie; Donnée spatiale; Modèle; Modélisation; Spectromètre; Analyse statistique; Distribution spatiale; Répartition spatiale; Caractéristique sol; Résolution spatiale; Carte; Matière organique; Couche arable; Imagerie hyperspectrale; Capteur mesure; Luxembourg</FD>
  <FG>Europe Ouest; Europe</FG>
  <ED>organic carbon; Agricultural soil; Cultivated field; remote sensing; airborne methods; Hyperspectral imaging sensor; reflectance; spectroscopy; Spatial data; models; Modeling; Spectrometer; statistical analysis; spatial distribution; Spatial distribution; Property of soil; spatial resolution; maps; organic materials; Top soil; Hyperspectral imagery; measurement sensor; Luxembourg</ED>
  <EG>Western Europe; Europe</EG>
  <SD>Carbono orgánico; Suelo agrícola; Campo cultivado; Detección a distancia; Método aerotransportado; Sensor hiperespectral de formación de imágenes; Poder reflector; Espectrometría; Dato espacial; Modelo; Modelización; Espectrómetro; Distribución espacial; Distribución espacial; Característica suelo; Mapa; Materia orgánica; Capa arable; Imaginería hiperespectral; Luxemburgo</SD>
  <LO>INIST-3607.354000180786920040</LO>
  <ID>10-0391942</ID>
</server>
<server>
  <NO>: PASCAL 10-0478256 INIST</NO>
  <FT>Rouille brune du blé, un modèle pour évaluer les risques</FT>
  <AU>MOUSSA (Jarroudi); GIRAUD (F.); TYCHON (B.); HOFFMANN (L.); MARAITE (H.); DELFOSSE (P.)</AU>
  <AF>Université de Liège, Département en sciences et gestion de l'environnement, 185, avenue de Longwy/6700 Arlon/Belgique (1 aut., 3 aut.); Staphyt/Biorizon, Rue Magendie/Bor/France (2 aut.); Centre de recherche public - Gabriel Lippmann, Département Environnement et Agro-biotechnologies (EVA), 41, rue du Brill/4422 Belvaux/Luxembourg (2 aut., 4 aut., 6 aut.); Unité de phytopathologie, Université catholique de Louvain (UCL), Croix du Sud 2/3/1348 Louvain-la-Neuve/Belgique (5 aut.)</AF>
  <DT>Publication en série; Niveau analytique</DT>
  <SO>Phytoma, la défense des végétaux; ISSN 1164-6993; France; Da. 2010; No. 637; Pp. 9-12; Abs. anglais; Bibl. 1/4 p.</SO>
  <LA>Français</LA>
  <FA>L'article présente un outil de prévision de la rouille brune au G.-D. de Luxembourg. De 2000 à 2003, cette maladie apparaissait à la fin de l'épiaison, mais depuis 2003, elle apparaît de plus en plus tôt (GS45 stade gonflement). Cette plus grande précocité est probablement liée à des températures printanières supérieures par rapport à la normale<sub>197</sub>1-2000. Une analyse des données météorologiques nocturnes et des données d'observation de la maladie sur quatre sites expérimentaux (Everlange, Christnach, Burmerange et Reuler), entre 2000 et 2003, a révélé une forte corrélation positive entre d'une part la prédiction de la maladie basée sur le critère d'au moins 12 heures nocturnes consécutives à température comprise entre 8 et 16 °C et humidité supérieure à 60 % et, d'autre part, la maladie observée sur la F1 (R = 0,93 ; P &lt; 0,05) et la F2 (R = 0,87 ; P &lt; 0,05). Les sorties de ce modèle qui a été développé sur la base d'une approche stochastique ont été utilisées dans les bulletins d'avertissements diffusés conjointement par le Centre de Recherche Public-Gabriel Lippmann et l'Université de Liège-Campus d'Arlon à partir de<sub>2004</sub>. La mise en application du modèle a montré un taux de réussite oscillant entre 80 et 85 % pour la simulation de la rouille brune. L'effort se poursuit pour spatialiser les sorties du modèle sur tout le territoire luxembourgeois et faciliter son utilisation par tous les vulgarisateurs agricoles.</FA>
  <CC>002A34G</CC>
  <FD>Rouille parasitaire; Evaluation; Risque; Elément météorologique; Simulation; Phytopathologie; Phytopathogène; Puccinia triticina; Blé</FD>
  <FG>Basidiomycota; Fungi; Céréale; Mycose; Infection</FG>
  <ED>Parasitic rust; Evaluation; Risk; Meteorological variable; Simulation; Plant pathology; Plant pathogen; Puccinia triticina; Wheat</ED>
  <EG>Basidiomycota; Fungi; Cereal; Mycosis; Infection</EG>
  <SD>Roya parasitaria; Evaluación; Riesgo; Elemento meteorológico; Simulación; Fitopatología; Fitopatógeno; Puccinia triticina; Trigo</SD>
  <LO>INIST-2482.354000192441520010</LO>
  <ID>10-0478256</ID>
</server>
<server>
  <NO>: PASCAL 11-0146207 INIST</NO>
  <FT>Prévoir la septoriose un modèle belge au Luxembourg: Modélisation et simulation révisionnelle de la septoriose des feuilles par Proculture pour une gestion durabte du blé d'hiver</FT>
  <AU>JARROUDI (Moussa El); GIRAUD (Frédéric); TYCHON (B.); HOFFMANN (L.); MARAITE (H.); DELFOSSE (P.)</AU>
  <AF>Université de Liège, Département en Sciences et Gestion de l'Environnement 185, avenue de Longwy/6700 Arlon/Belgique (1 aut., 3 aut.); Staphyt/Biorizon Rue Magendie/Bordeaux Montesquieu/33650 Martillac/France (2 aut.); Centre de recherche public Gabriel-Lippmann, Département environnement et agro-biotechnologies (EVA), 41, rue du Brill/4422 Belvaux/Luxembourg (2 aut., 4 aut., 6 aut.); Unité de Phytopathologie, Université catholique de Louvain (UCL), Croix du Sud 2/3/1348 Louvain-la-Neuve/Belgique (5 aut.)</AF>
  <DT>Publication en série; Niveau analytique</DT>
  <SO>Phytoma, la défense des végétaux; ISSN 1164-6993; France; Da. 2011; No. 642; Pp. 43-46; Abs. anglais</SO>
  <LA>Français</LA>
  <FA>Un modèle de simulation « Proculture » a été développé en Belgique puis au Luxembourg pour définir en temps réel le risque d'apparition de Septoria tritici sur les feuilles supérieures du blé d'hiver pendant la montaison. La particularité de ce modèle de simulation est sa capacité d'analyser les interactions entre la formation des feuilles et la progression de S. tritici sur les feuilles déjà formées. Le couplage du module de maladie avec un module de croissance permet la simulation du développement de la maladie à l'échelle parcellaire. Cette plate-forme décisionnelle aide les agriculteurs déterminerle moment optimal pour un traitement fongicide quand le risque élevé d'infection de F3 (F1 est la dernière feuille formée) est atteint. La calibration et la validation de « Proculture » ont été réalisées entre 2000 et 2002. Avec un taux de réussite oscillant entre 8<sub>5</sub>% et95 %, le logiciel semble être un outil indispensable pour une agriculture de précision à l'échelle parcellaire au Grand-Duché de Luxembourg. À partir de 2004, ce logiciel a été utilisé dans des bulletins d'avertissements diffusés hebdomadairement aux agriculteurs. Au Gutland (sud du Grand-Duché), la rentabilité du traitement recommandé par le modèle entre 2003 et 2009 est 80 % supérieure aux autres traitements. Dans l'Oesling (au nord) où la septoriose est très faible, ce logiciel a permis de guider les agriculteurs à réduire les charges inutiles de traitement. Entre 2003 et 2009, le traitement contre la septoriose a seulement été recommandé une fois sur base du modèle. Ceci laisse supposer que ce logiciel contribue en quelque sorte à l'encouragement des cultures bios pour certains sites et, en tout cas, à favoriser les principes de lutte intégrée de façon générale.</FA>
  <CC>002A34G; 002A32</CC>
  <FD>Mycose; Modélisation; Simulation; Système aide décision; Validation; Phytopathologie; Modèle; Triticum aestivum; Septoria tritici; Luxembourg; Plante en C3</FD>
  <FG>Infection; Gramineae; Monocotyledones; Angiospermae; Spermatophyta; Fungi Imperfecti; Fungi; Europe; Plante céréalière; Type C3; Phytopathogène; Végétal; Europe Ouest; Zone tempérée</FG>
  <ED>Mycosis; Modeling; Simulation; Decision support system; Validation; Plant pathology; Models; Triticum aestivum; Septoria tritici; Luxembourg</ED>
  <EG>Infection; Gramineae; Monocotyledones; Angiospermae; Spermatophyta; Fungi Imperfecti; Fungi; Europe; Cereal crop; C3-Type; Plant pathogen; Vegetals; Western Europe; Temperate zone</EG>
  <SD>Micosis; Modelización; Simulación; Sistema ayuda decisíon; Validación; Fitopatología; Modelo; Triticum aestivum; Septoria tritici; Luxemburgo</SD>
  <LO>INIST-2482.354000190704740100</LO>
  <ID>11-0146207</ID